Withanolide A prevents neurodegeneration by modulating hippocampal glutathione biosynthesis during hypoxia.

Withania somnifera root extract has been used traditionally in ayurvedic system of medicine as a memory enhancer. Present study explores the ameliorative effect of withanolide A, a major component of withania root extract and its molecular mechanism against hypoxia induced memory impairment. Withano...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Iswar Baitharu, Vishal Jain, Satya Narayan Deep, Sabita Shroff, Jayanta Kumar Sahu, Pradeep Kumar Naik, Govindasamy Ilavazhagan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Online Access:http://europepmc.org/articles/PMC4195593?pdf=render