Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Summary: Pancreatic ductal adenocarcinoma (PDAC) exhibits an immunosuppressive tumor microenvironment (TME) contributing to its therapeutic resistance. Following our previous studies, we report that mast cells infiltrating the PDAC TME foster this immunosuppression and desmoplasia. Mast cell infiltr...

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出版年:	iScience
主要な著者:	Ying Ma, Xiangqin Zhao, Jingyan Feng, Suimin Qiu, Baoan Ji, Lu Huang, Patrick Hwu, Craig D. Logsdon, Huamin Wang
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2024-11-01
主題:	Molecular biology Neuroscience Immunology Cancer
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2589004224023101