Liver X Receptor α Inhibits Osteosarcoma Cell Proliferation through Up-Regulation of FoxO1

Background: Osteosarcoma is the most common primary bone malignancy of adolescents and young adults. Methods: We analyzed liver X receptor α (LXRα) mRNA expression in 16 pairs of human osteosarcoma tissues and adjacent noncancerous tissues. Moreover, we investigated LXRα's potential role in reg...

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Bibliographic Details
Published in:Cellular Physiology and Biochemistry
Main Authors: Yue-wen Chang, Yong-fang Zhao, Yue-long Cao, Xin-feng Gu, Zhi-qiang Li, Shu-qiang Wang, Jin-hao Miao, Hong-sheng Zhan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-07-01
Subjects:
Osteosarcoma
LXRα
FoxO1
Transcription
Online Access:http://www.karger.com/Article/FullText/350134

Internet

http://www.karger.com/Article/FullText/350134

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