The functional significance of vascular DNA hypermethylation in atherosclerosis: a historical perspective

A decade ago, independent mechanistic and descriptive epigenomics data demonstrated for the first time that vascular DNA hypermethylation is a landmark of and causal factor in human and murine atherosclerosis. Since then, a flurry of converging evidence has assigned a prominent role to vascular DNA...

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Bibliographic Details
Published in:Frontiers in Pharmacology
Main Author: Silvio Zaina
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1562674/full