NAMPT‐Driven M2 Polarization of Tumor‐Associated Macrophages Leads to an Immunosuppressive Microenvironment in Colorectal Cancer

Abstract Nicotinamide phosphoribosyltransferase (NAMPT) is a metabolic enzyme with key roles in inflammation. Previous studies have examined the consequences of its upregulated expression in cancer cells themselves, but studies are limited with respect to its role in the other cells within the tumor...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Sun Mi Hong, A‐Yeon Lee, Byeong‐Ju Kim, Jeong‐Eun Lee, Su‐Yeon Seon, Yu‐Jin Ha, Jestlin Tianthing Ng, Gyesoon Yoon, Su Bin Lim, Michael J. Morgan, Jong‐Ho Cha, Dakeun Lee, You‐Sun Kim
Format:	Article
Language:	English
Published:	Wiley 2024-04-01
Subjects:	CRC HIF‐1α M2‐like TAMs NAMPT STING
Online Access:	https://doi.org/10.1002/advs.202303177