Single intranasal immunization with a high dose of influenza vector protects against infection with heterologous influenza virus and SARS-CoV-2 in ferrets and hamsters

BACKGROUND: The challenge of vaccine effectiveness against viruses that undergo constant antigenic changes during evolution is currently being addressed by updating vaccine formulations to match circulating strains. However, this approach proves ineffective if a virus undergoes antigenic drift and...

Full description

Bibliographic Details

Published in:	Microbiology Independent Research Journal
Main Authors:	Andrej Egorov, Artem A. Krokhin, Irina A. Leneva, Pavel Korabliov, Pavelas Loiteris, Vladimir E. Nebolsin
Format:	Article
Language:	English
Published:	Doctrine 2024-02-01
Online Access:	https://www.scienceopen.com/hosted-document?doi=10.18527/2024111024