Paternal age and offspring congenital heart defects: a national cohort study.

Paternal age has been associated with offspring congenital heart defects (CHDs), which might be caused by increased mutations in the germ cell line because of cumulated cell replications. Empirical evidences, however, remain inconclusive. Furthermore, it is unknown whether all subtypes of CHDs are a...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Xiu Juan Su, Wei Yuan, Guo Ying Huang, Jørn Olsen, Jiong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Online Access:http://europepmc.org/articles/PMC4373953?pdf=render