Molecular studies of phages-Klebsiella pneumoniae in mucoid environment: innovative use of mucolytic agents prior to the administration of lytic phages

Mucins are important glycoproteins that form a protective layer throughout the gastrointestinal and respiratory tracts. There is scientific evidence of increase in phage-resistance in the presence of mucin for some bacterial pathogens. Manipulation in mucin composition may ultimately influence the e...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Olga Pacios, Lucía Blasco, Concha Ortiz Cartagena, Inés Bleriot, Laura Fernández-García, María López, Antonio Barrio-Pujante, Felipe Fernández Cuenca, Belén Aracil, Jesús Oteo-Iglesias, María Tomás
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	Klebsiella pneumoniae lytic bacteriophages phage resistance co-evolution mucin n-acetyl cysteine
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1286046/full