The integrated single-cell analysis interpret the lactate metabolism-driven immune suppression in triple-negative breast cancer

Abstract Background Individuals with triple-negative breast cancer (TNBC) exhibit elevated lactate levels, which offers a valuable lead for investigating the molecular mechanisms underlying the tumor microenvironment (TME) and identifying more efficacious treatments. Methods TNBC samples were classi...

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Bibliographic Details
Published in:Discover Oncology
Main Authors: Xinhai Gao, Tianhua Wang, Cun Liu, Ye Li, Wenfeng Zhang, Minpu Zhang, Yan Yao, Chundi Gao, Ruijuan Liu, Changgang Sun
Format: Article
Language:English
Published: Springer 2025-05-01
Subjects:
Triple-negative breast cancer
Lactate
Tumor microenvironment
Online Access:https://doi.org/10.1007/s12672-025-02605-0

Internet

https://doi.org/10.1007/s12672-025-02605-0

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