Non-cognate ligands of hepatitis C virus envelope broadly neutralizing antibodies induce virus-neutralizing sera in mice

IntroductionThe persistent rise in new Hepatitis C virus (HCV) infections threatens WHO efforts to eliminate HCV infection by 2030. Although direct-acting antiviral (DAA) drugs are efficacious, access remains limited, reinfections occur, and perinatal infections continue to pose long-term complicati...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Stephen Ian Walimbwa, Shiv Bharadwaj, Petr Kosztyu, Lucie Vankova, Milan Kuchar, Eliska Kopecna, Roman Effenberg, Lukas Drasar, Leona Raskova Kafkova, Petr Maly, Milan Raska
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	hepatitis C vaccine mimotope broadly neutralizing antibodies myomedins protein mimicry
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1624299/full