Staphylococcus aureus α-toxin impairs early neutrophil localization via electrogenic disruption of store-operated calcium entry

Summary: The pore-forming S. aureus α-toxin (Hla) contributes to virulence and disease pathogenesis. While high concentrations of toxin induce cell death, neutrophils exhibit relative resistance to lysis, suggesting that the action of Hla may not be solely conferred by lytic susceptibility. Using in...

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出版年:	Cell Reports
主要な著者:	Fan Yang, Mingyi Suo, Homayemem Weli, Mason Wong, Alex Junidi, Celeste Cummings, Ryan Johnson, Kiara Mallory, Annie Y. Liu, Zev J. Greenberg, Laura G. Schuettpelz, Mark J. Miller, Cliff J. Luke, Gwendalyn J. Randolph, Bernd H. Zinselmeyer, Juliane Bubeck Wardenburg, Regina A. Clemens
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-11-01
主題:	CP: Microbiology CP: Cell biology
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211124723014067