Role of Lactate Dehydrogenase in Tumor Metabolism and Progress of LDH-targeted Drugs

Abnormal energy metabolism is one of the main hallmarks of cancer. Studies have shown that tumor cells, even in the presence of oxygen, favored glycolysis to produce lactic acid and a small amount of ATP with the help of LDHA in the cytosol (the famous Warburg effect). The excessive lactate is then...

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Bibliographic Details
Published in:Zhongliu Fangzhi Yanjiu
Main Authors: QIU Jinmei, GONG Juan, XIE Qingchi, XIE Zhizhong
Format: Article
Language:Chinese
Published: Magazine House of Cancer Research on Prevention and Treatment 2020-12-01
Subjects:
lactate
lactic dehydrogenase
warburg effect
pyruvate metabolism
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2020.20.0279.htm

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http://html.rhhz.net/ZLFZYJ/html/8578.2020.20.0279.htm

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