7-Ketocholesterol Induces Lipid Metabolic Reprogramming and Enhances Cholesterol Ester Accumulation in Cardiac Cells

7-Ketocholesterol (7KCh) is a major oxidized cholesterol product abundant in lipoprotein deposits and atherosclerotic plaques. Our previous study has shown that 7KCh accumulates in erythrocytes of heart failure patients, and further investigation centered on how 7KCh may affect metabolism in cardiom...

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Bibliographic Details

Published in:	Cells
Main Authors:	Mei-Ling Cheng, Hsiang-Yu Tang, Pei-Ting Wu, Cheng-Hung Yang, Chi-Jen Lo, Jui-Fen Lin, Hung-Yao Ho
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Subjects:	7-ketocholesterol cholesteryl esters cardiac cells
Online Access:	https://www.mdpi.com/2073-4409/10/12/3597