Angiopoietin-2 adsorption attempt with the cytokine adsorber cytosorb in critically ill patients

Abstract Angiopoietin 2 (Ang-2) is a growth factor in angiogenesis, causing pericyte migration and vascular regression, leading to increased vascular permeability. Inflammatory mediators, hypoxia, hyperglycaemia and cancer stimulate its secretion. Particularly in sepsis, high Ang-2 levels appear to...

Full description

Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Helen Graf, Caroline Gräfe, Michael Paal, Katarina Habler, Alice Ewert, Wolfgang Wilfert, Uwe Liebchen, Martin Bender, Danilo Hackner, Christina Scharf
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-10-01
Subjects:	Angiopoietin-2 (Ang-2) Endothelial dysfunction Sepsis Rhabdomyolysis Cytosorb
Online Access:	https://doi.org/10.1038/s41598-025-21215-y