Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies

Abstract RNA binding proteins (RBPs) are key regulators of RNA processing and cellular function. Technologies to discover RNA targets of RBPs such as TRIBE (targets of RNA binding proteins identified by editing) and STAMP (surveying targets by APOBEC1 mediated profiling) utilize fusions of RNA base-...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Hugo C. Medina-Munoz, Eric Kofman, Pratibha Jagannatha, Evan A. Boyle, Tao Yu, Krysten L. Jones, Jasmine R. Mueller, Grace D. Lykins, Andrew T. Doudna, Samuel S. Park, Steven M. Blue, Brodie L. Ranzau, Rahul M. Kohli, Alexis C. Komor, Gene W. Yeo
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Online Access:https://doi.org/10.1038/s41467-024-45009-4