Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation

Accumulating evidence indicates that bacterial metabolism plays an important role in virulence. Acetyl phosphate (AcP), the high-energy intermediate of the phosphotransacetylase-acetate kinase pathway, is the major acetyl donor in E. coli. PhoP is an essential transcription factor for bacterial viru...

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Bibliographic Details

Published in:	Emerging Microbes and Infections
Main Authors:	Jie Ren, Yu Sang, Ran Qin, Yang Su, Zhongli Cui, Zhiguo Mang, Hao Li, Shaoyong Lu, Jian Zhang, Sen Cheng, Xiaoyun Liu, Jixi Li, Jie Lu, Wenjuan Wu, Guo-Ping Zhao, Feng Shao, Yu-Feng Yao
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2019-01-01
Subjects:	Acetyl phosphate acetylation phosphorylation PhoP virulence metabolism
Online Access:	https://www.tandfonline.com/doi/10.1080/22221751.2018.1558963