A comparative study of the Au-catalyzed cyclization of hydroxy-substituted allylic alcohols and ethers

The Au(I)-catalyzed cyclization of hydroxyallylic ethers to form tetrahydropyrans is reported. Employing (acetonitrile)[(o-biphenyl)di-tert-butylphosphine]gold(I) hexafluoroantimonate, the cyclization reactions were complete within minutes to hours, depending on the substrate. The reaction progress...

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Bibliographic Details

Published in:	Beilstein Journal of Organic Chemistry
Main Authors:	Berenger Biannic, Thomas Ghebreghiorgis, Aaron Aponick
Format:	Article
Language:	English
Published:	Beilstein-Institut 2011-06-01
Subjects:	allylic alcohol allylic ether Au-catalyzed SN2' tetrahydropyran
Online Access:	https://doi.org/10.3762/bjoc.7.91