The development of a novel multiepitope vaccine targeting the secretion systems of Pseudomonas aeruginosa using a reverse vaccinology and immunoinformatic strategy

Abstract The emergence of multidrug-resistant Pseudomonas aeruginosa strains poses a significant public health risk due to the high morbidity and mortality associated with invasive infections. Despite extensive efforts, vaccine candidates targeting P. aeruginosa have failed in clinical trials, and t...

Full description

Bibliographic Details

Published in:	Discover Applied Sciences
Main Authors:	Tohid Piri-Gharaghie, Marjaneh Ebrahimi, Behnaz Dehganzad, Zahra Seraj
Format:	Article
Language:	English
Published:	Springer 2025-04-01
Subjects:	Pseudomonas aeruginosa Reverse vaccinology Immunogenic target
Online Access:	https://doi.org/10.1007/s42452-025-06768-x