Deriving GWAS summary estimates for paternal smoking in UK biobank: a GWAS by subtraction

Abstract Objective To use genome-wide association study (GWAS) by subtraction, a method for deriving novel GWASs from existing summary statistics, to derive genome-wide summary statistics for paternal smoking. Result A GWAS by subtraction was implemented using a weighted linear model that defined th...

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Bibliographic Details

Published in:	BMC Research Notes
Main Authors:	Benjamin Woolf, Hannah M. Sallis, Marcus R. Munafò, Dipender Gill
Format:	Article
Language:	English
Published:	BMC 2023-07-01
Subjects:	GWAS-by-subtraction Intergenerational Mendelian randomisation Family GWAS Genome Wide association studies
Online Access:	https://doi.org/10.1186/s13104-023-06438-4