Pan-cancer screening by circulating tumor DNA (ctDNA) – recent breakthroughs and chronic pitfalls

Early detection is crucial for optimal treatment and prognosis of cancer. New approaches for pan-cancer screening comprise the comprehensive characterization of circulating tumor DNA (ctDNA) in plasma by next generation sequencing and molecular profiling of mutations and methylation patterns, as wel...

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Bibliographic Details

Published in:	Journal of Laboratory Medicine
Main Authors:	Holdenrieder Stefan, Ungerer Vida, Oberhofer Angela, Bronkhorst Abel Jacobus
Format:	Article
Language:	English
Published:	De Gruyter 2022-08-01
Subjects:	cancer ctdna early detection fragment analysis liquid profiling methylation mutations next generation sequencing screening
Online Access:	https://doi.org/10.1515/labmed-2022-0029