Deoxycholic acid aggravates necrotizing enterocolitis through downregulation of mesenchymal-epithelial transition factor expression

Bile acids are closely associated with necrotizing enterocolitis (NEC), and their accumulation has cytotoxic effects on cells. However, the specific bile acid subtype involved in NEC and its underlying mechanisms remains poorly understood, limiting the therapeutic potential of bile acids as treatmen...

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Bibliographic Details

Published in:	Brazilian Journal of Medical and Biological Research
Main Authors:	Hongfu Li, Jiahao Lai, Dongfan Xiao, Dabin Huang, Yinchun Zhang, Xia Gu, Fei Li, Hu Hao
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2024-11-01
Subjects:	Neonatal necrotizing enterocolitis Infant Newborn Intestinal epithelial cell Deoxycholic acid
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100691&lng=en&tlng=en