Insights into the Structure and Function of the Pex1/Pex6 AAA-ATPase in Peroxisome Homeostasis

The AAA-ATPases Pex1 and Pex6 are required for the formation and maintenance of peroxisomes, membrane-bound organelles that harbor enzymes for specialized metabolism. Together, Pex1 and Pex6 form a heterohexameric AAA-ATPase capable of unfolding substrate proteins via processive threading through a...

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Bibliographic Details
Published in:Cells
Main Authors: Ryan M. Judy, Connor J. Sheedy, Brooke M. Gardner
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Subjects:
peroxisomes
organelle biogenesis
AAA-ATPase
translocation
PEX1
PEX6
Online Access:https://www.mdpi.com/2073-4409/11/13/2067

Internet

https://www.mdpi.com/2073-4409/11/13/2067

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