DISC1 Regulates Mitochondrial Trafficking in a Miro1-GTP-Dependent Manner

The disrupted in schizophrenia 1 (DISC1) protein is implicated in major mental illnesses including schizophrenia and bipolar disorder. A key feature of psychiatric disease is aberrant synaptic communication. Correct synaptic transmission is dependent on spatiotemporally regulated energy provision an...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Rosalind Norkett, Flavie Lesept, Josef T. Kittler
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-06-01
Subjects:	mitochondria trafficking schizophrenia DISC1 miro GTPase
Online Access:	https://www.frontiersin.org/article/10.3389/fcell.2020.00449/full