Whole-body MRI-based long-term evaluation of pediatric NF1 patients without initial tumor burden with evidence of newly developed peripheral nerve sheath tumors

Abstract Background Patients with neurofibromatosis type 1 (NF1) can develop plexiform neurofibromas (PN). Large tumor burden is a predictor for the development of malignant peripheral nerve sheath tumors. Whole-body magnetic resonance imaging (WB-MRI) is the recommended imaging method for the evalu...

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Bibliographic Details

Published in:	Orphanet Journal of Rare Diseases
Main Authors:	Marie-Lena Schmalhofer, Said Farschtschi, Lan Kluwe, Victor Felix Mautner, Gerhard Adam, Lennart Well, Inka Ristow
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Subjects:	Peripheral nerve sheath tumor NF1 in children Plexiform neurofibromas Magnetic resonance imaging MRI-based long-term evaluation
Online Access:	https://doi.org/10.1186/s13023-024-03420-6