Hypoxia, vascular smooth muscles and endothelium

Hypoxia, or the lack of oxygen, has multiple impacts on the vascular system. The major molecular sensors for hypoxia at the cellular level are hypoxia inducible factor and heme oxygenase. Hypoxia also acts on the vasculature directly conveying its damaging effects through disruption of the control o...

Full description

Bibliographic Details
Published in:Acta Pharmaceutica Sinica B
Main Authors: Calvin K. Chan, Paul M. Vanhoutte
Format: Article
Language:English
Published: Elsevier 2013-02-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383512001669