NK Cells from RAG- or DCLRE1C-Deficient Patients Inhibit HCMV

The recombination-activating genes (RAGs) and the DNA cross-link repair 1C gene (DCLRE1C) encode the enzymes RAG1, RAG2 and Artemis. They are critical components of the V(D)J recombination machinery. V(D)J recombination is well known as a prerequisite for the development and antigen diversity of T a...

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Bibliographic Details
Published in:Microorganisms
Main Authors: Zeguang Wu, Narmadha Subramanian, Eva-Maria Jacobsen, Kerstin Laib Sampaio, Johannes van der Merwe, Manfred Hönig, Thomas Mertens
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Subjects:
human cytomegalovirus
natural killer cell
severe combined immunodeficiency
Online Access:https://www.mdpi.com/2076-2607/7/11/546

Internet

https://www.mdpi.com/2076-2607/7/11/546

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