Getting personal with epigenetics: towards individual-specific epigenomic imputation with machine learning

Abstract Epigenetic modifications are dynamic mechanisms involved in the regulation of gene expression. Unlike the DNA sequence, epigenetic patterns vary not only between individuals, but also between different cell types within an individual. Environmental factors, somatic mutations and ageing cont...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nature Communications
المؤلفون الرئيسيون: Alex Hawkins-Hooker, Giovanni Visonà, Tanmayee Narendra, Mateo Rojas-Carulla, Bernhard Schölkopf, Gabriele Schweikert
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2023-08-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-023-40211-2