Depletion of regulatory T cells enhances the T cell response induced by the neoantigen vaccine with weak immunogenicity

Background: The neoantigen vaccine has remarkable potential in treating advanced cancer due to its tumor specificity and ability to bypass central tolerance mechanisms. However, numerous neoantigens show poor immunogenicity, and the immune inhibitory factors of present in both tumors and tumor-drain...

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書誌詳細

出版年:	Neoplasia: An International Journal for Oncology Research
主要な著者:	Ruichen Huang, Qiao Zhou, Jiajun Liu, Yang Xia, Yang Jiao, Bi Zhao, Tangtao Feng, Haosu Zhou, Xiuyan Song, Hao Qin, Jun Wang, Lan Cheng, Yunye Ning, Qinying Sun, Yanfang Liu, Xiaoping Su, Yuchao Dong, Wei Zhang
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2025-01-01
主題:	Solid tumor Neoantigen Cancer vaccine Regulatory T cell
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S1476558624001295