Development and Evaluation of a Water-Free In Situ Depot Gel Formulation for Long-Acting and Stable Delivery of Peptide Drug ACTY116

In situ depot gel is a type of polymeric long-acting injectable (pLAI) drug delivery system; compared to microsphere technology, its preparation process is simpler and more conducive to industrialization. To ensure the chemical stability of peptide ACTY116, we avoided the use of harsh conditions suc...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Yingxin Xiong, Zhirui Liu, Yuanqiang Wang, Jiawei Wang, Xing Zhou, Xiaohui Li
Format:	Article
Language:	English
Published:	MDPI AG 2024-05-01
Subjects:	peptide in situ depot gel long-acting injectable stability molecular dynamics
Online Access:	https://www.mdpi.com/1999-4923/16/5/620