Downregulation of ubiquitous microRNA-320 in hepatocytes triggers RFX1-mediated FGF1 suppression to accelerate MASH progression

Metabolic dysfunction-associated steatohepatitis (MASH), a severe type of metabolic dysfunction-associated steatotic liver disease (MASLD), is a leading etiology of end-stage liver disease worldwide, posing significant health and economic burdens. microRNA-320 (miR-320), a ubiquitously expressed and...

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Bibliographic Details

Published in:	Acta Pharmaceutica Sinica B
Main Authors:	Liu Yang, Wenjun Li, Yingfen Chen, Ru Ya, Shengying Qian, Li Liu, Yawen Hao, Qiuhong Zai, Peng Xiao, Seonghwan Hwang, Yong He
Format:	Article
Language:	English
Published:	Elsevier 2025-08-01
Subjects:	miR-320 MASLD RFX1 FGF1 AMPK
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211383525004101