Zebrafish functional xenograft vasculature platform identifies PF-502 as a durable vasculature normalization drug

Summary: Tumor vasculature often exhibits disorder and inefficiency. Vascular normalization offers potential for alleviating hypoxia and optimizing drug delivery in tumors. However, identifying effective agents is hindered by a lack of robust screening. We aimed to establish a comprehensive method u...

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Bibliographic Details

Published in:	iScience
Main Authors:	Jian Zhong, Chaoxin Xiao, Qin Chen, Xiangyu Pan, Tongtong Xu, Yiyun Wang, Wanting Hou, Lu Liu, Fujun Cao, Yulin Wang, Xiaoying Li, Lin Zhou, Hanshuo Yang, Yu Yang, Chengjian Zhao
Format:	Article
Language:	English
Published:	Elsevier 2023-09-01
Subjects:	Biological sciences Molecular biology Cell biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223018114