Unraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states

Abstract Objectives This study aims to elucidate the transcriptomic signatures and dysregulated pathways in patients with Systemic Lupus Erythematosus (SLE), with a particular focus on those persisting during disease remission. Methods We conducted bulk RNA-sequencing of peripheral blood mononuclear...

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Bibliographic Details

Published in:	Arthritis Research & Therapy
Main Authors:	Frank Qingyun Wang, Li Shao, Xiao Dang, Yong-Fei Wang, Shuxiong Chen, Zhongyi Liu, Yujing Mao, Yuping Jiang, Fei Hou, Xianghua Guo, Jian Li, Lili Zhang, Yuting Sang, Xuan Zhao, Ruirui Ma, Kai Zhang, Yanfang Zhang, Jing Yang, Xiwu Wen, Jiong Liu, Wei Wei, Chuanpeng Zhang, Weiyang Li, Xiao Qin, Yao Lei, Hong Feng, Xingtian Yang, Chun Hing She, Caicai Zhang, Huidong Su, Xinxin Chen, Yu Lung Lau, Qingjun Wu, Bo Ban, Qin Song, Wanling Yang
Format:	Article
Language:	English
Published:	BMC 2024-05-01
Subjects:	Systemic lupus erythematosus Remission PBMC Gene signatures
Online Access:	https://doi.org/10.1186/s13075-024-03327-4