Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction

Neuropeptides and neurotrophins are stored in and released from dense core vesicles (DCVs). While DCVs and synaptic vesicles (SVs) share fundamental SNARE/SM proteins for exocytosis, a detailed understanding of DCV exocytosis remains elusive. We recently identified the RAB3-RIM1 pathway to be essent...

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發表在:	eLife
Main Authors:	Adlin Abramian, Rein I Hoogstraaten, Fiona H Murphy, Kathryn F McDaniel, Ruud F Toonen, Matthijs Verhage
格式:	Article
語言:	英语
出版:	eLife Sciences Publications Ltd 2024-10-01
主題:	rabphilin-3A neuropeptide release dense core vesicles SNAP25 hippocampal mouse neurons
在線閱讀:	https://elifesciences.org/articles/95371