Development and Characterization of Paclitaxel-loaded PLGA Nanoparticles and Evaluation of Cytotoxicity on MCF-7 Cell Line by MTT Assay

Paclitaxel (PTX), cytotoxic agent extracted from Taxus brevifolia has significant antineoplastic activity against breast cancer. Poly d,l-lactide-co-glycolide (PLGA) has been widely used for the preparation of nanoparticles carrying cytotoxic drug agents. The aim of this study was to evaluate the ef...

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Bibliographic Details

Published in:	Proceedings
Main Authors:	Merve Çelik Tekeli, Çiğdem Yücel, Sedat Ünal, Gökçe Şeker Karatoprak, Yeşim Aktaş, Erem Bilensoy
Format:	Article
Language:	English
Published:	MDPI AG 2017-11-01
Subjects:	PLGA nanoparticle MCF-7 MTT Cytotoxicity
Online Access:	https://www.mdpi.com/2504-3900/1/10/1030