Release kinetics of metronidazole from 3D printed silicone scaffolds for sustained application to the female reproductive tract

Sustained vaginal administration of antibiotics or probiotics has been proposed to improve treatment efficacy for bacterial vaginosis. 3D printing has shown promise for development of systems for local agent delivery. In contrast to oral ingestion, agent release kinetics can be fine-tuned by the 3D...

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Bibliographic Details

Published in:	Biomedical Engineering Advances
Main Authors:	Sydney E. Herold, Anthony J. Kyser, Margaret G. Orr, Mohamed Y. Mahmoud, Warren G. Lewis, Amanda L. Lewis, Jill M. Steinbach-Rankins, Hermann B. Frieboes
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Subjects:	Metronidazole 3D printed scaffolds Silicone scaffolds Drug release kinetics Bacterial vaginosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667099223000087