A collection of four integration-free iPSC lines derived from diagnosed sporadic Alzheimer's disease patients with different APOE alleles

Genetic polymorphism of apolipoprotein E (APOE) confers differential susceptibility to late-onset Alzheimer's disease (LOAD). The ε3 allele of APOE, the most common isoform, does not represent a risk factor for LOAD. In contrast, the ε4 allele is the strongest genetic risk factor for this disea...

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Bibliographic Details

Published in:	Stem Cell Research
Main Authors:	Eva Díaz-Guerra, Elena P. Moreno-Jiménez, Itziar de Rojas, César Rodríguez, Eva Rodríguez-Traver, Esther Arribas-González, María Orera, Isabel Hernández, Agustín Ruiz, Carlos Vicario
Format:	Article
Language:	English
Published:	Elsevier 2019-08-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506119301527