Differential expression and functional analysis of circular RNAs and m6A modifications in children with Philadelphia chromosome-positive acute lymphoblastic leukemia

Abstract Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukaemia (ALL) in childhood is associated with dismal outcomes, in large part due to challenges in diagnosis and monitoring therapeutic efficacy. Recent studies suggest that circular RNAs (circRNAs) are potential diagnostic and pro...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Lichun Xie, Ye Xu, Chuiqin Fan, Maochuan Liao, Guichi Zhou, Chen Fen, Lian Ma, Fei-Qiu Wen
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-04-01
Subjects:	Circular RNA Philadelphia chromosome-positive acute lymphoblastic leukaemia N6-methyladenosine
Online Access:	https://doi.org/10.1038/s41598-025-97345-0