A Minireview on BET Inhibitors: Beyond Bromodomain Targeting

Bromodomain and extra-terminal domain (BET) proteins are epigenetic readers that recognize the histone acetylation code and play a critical role in regulating gene transcription. Dysregulation of BET proteins is associated with a number of pathologies, including cancer, inflammation-related metaboli...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Mikhail S. Iudin, Yuri M. Khodarovich, Anna M. Varizhuk, Vladimir B. Tsvetkov, Vyacheslav V. Severov
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Subjects:
BET proteins
BET inhibitors
BET phosphorylation sites
extra-terminal domain
BRD4
IDR
Online Access:https://www.mdpi.com/2227-9059/13/3/594

Internet

https://www.mdpi.com/2227-9059/13/3/594

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