Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing
The nuclear factor erythroid 2-related factor 2 (NFE2L2, known as NRF2) regulates the expression of antioxidative and anti-inflammatory proteins. In order to investigate its impact during viral infections and testing of antiviral compounds, we applied CRISPR/Cas9 editing to eliminate NRF2 in the hum...
| Published in: | Stem Cell Research |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
|
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506123000764 |