Application of Native Ion MobilityMass Spectrometry in the Study of Protein Structure and Conformational Diseases

Native mass spectrometry (MS) enables the maintenance of intramolecular and intermolecular noncovalent interactions in the gas phase, thus can be used for characterization of proteins and protein complexes under the near “native” conditions. Ion mobility spectrometry (IMS) is a technique that separa...

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Bibliographic Details

Published in:	Zhipu Xuebao
Main Author:	ZHUANG Xiao-yu;BIAN Xin-yu;LIU Shu;LIU Zhi-qiang;SONG Feng-rui
Format:	Article
Language:	English
Published:	Editorial Board of Journal of Chinese Mass Spectrometry Society 2022-11-01
Subjects:	ion mobility-mass spectrometry （im-ms） protein structure and conformation protein misfolding conformational disease protein-ligand interaction
Online Access:	http://www.jcmss.com.cn/CN/article/openArticlePDF.jsp?attachType=PDF&id=3110