PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity

ABSTRACT Invasive candidiasis, primarily caused by Candida albicans, poses a significant threat to immunocompromised patients, with high mortality rates. Understanding how immune responses to Candida albicans are mounted and controlled is fundamental to developing new therapeutic strategies. Protein...

全面介紹

書目詳細資料

發表在:	mBio
Main Authors:	Bethany Allen, Ivy M. Dambuza, Susan H. Berry, Delyth M. Reid, Sam M. McVey, Martina Mesiarikova, Larissa John, Moira Davie, Christa P. Baker, J. Simon C. Arthur, Mirela Delibegovic, Gordon D. Brown, Heather M. Wilson
格式:	Article
語言:	英语
出版:	American Society for Microbiology 2025-10-01
主題:	macrophages Candida albicans protein tyrosine phosphatase 1B infections
在線閱讀:	https://journals.asm.org/doi/10.1128/mbio.01516-25