Protocol for evaluating neuronal activity and neurotransmitter release following amyloid-beta oligomer injections into the rat hippocampus

Summary: In Alzheimer’s disease, there is an imbalance in neurotransmitter release and altered neuronal activation. Here, we present a protocol approach to analyze neuronal activity by combining local field potential (LFP) recording with microdialysis within the same animal. We describe steps for me...

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Bibliographic Details

Published in:	STAR Protocols
Main Authors:	Vincent Hervé, Laurie Bonenfant, Mathilde Amyot, Rime Balafrej, Obai Bin Ka’B Ali, Habib Benali, Jonathan Brouillette
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Subjects:	Neuroscience Mass spectrometry Systems biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666166725001182