Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats

ObjectiveMoxifloxacin (MFLX) frequently induces dysglycemia when used in the treatment of infectious diseases, particularly in patients with diabetes. However, the mechanism through which MFLX affects host glucose metabolism remains unclear. This study aimed to investigate the possible mechanism und...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Yewen Sun, Yuchen Qu, Zhuan Yang, Bo Lv, Guanjun Wang, Kai Fan, Yuyuan Wang, Jie Pan, Ziyan Du, Yunli Yu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	bile acid moxifloxacin hyperglycemia gut microbiota GLP-1
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1569856/full