Gut microbiota-derived short-chain fatty acids mediate the antifibrotic effects of traditional Chinese medicine in diabetic nephropathy

Diabetic nephropathy (DN), a devastating microvascular complication affecting 40% of diabetic patients worldwide, represents the leading cause of end-stage renal disease (ESRD) and poses a substantial therapeutic challenge due to its complex pathogenesis involving progressive renal fibrosis. Note: T...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Haiyan Jiang, Xiaoran Wang, Wei Zhou, Zhili Huang, Wen Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	diabetic nephropathy renal fibrosis gut microbiota short-chain fatty acids traditional Chinese medicine gut–kidney axis
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1643515/full