Drug release from PLGA microparticles can be slowed down by a surrounding hydrogel

This study aimed to evaluate and better understand the potential impact that a layer of surrounding hydrogel (mimicking living tissue) can have on the drug release from PLGA microparticles. Ibuprofen-loaded microparticles were prepared with an emulsion solvent extraction/evaporation method. The drug...

詳細記述

書誌詳細

出版年:	International Journal of Pharmaceutics: X
主要な著者:	L.A. Lefol, P. Bawuah, J.A. Zeitler, J. Verin, F. Danede, J.F. Willart, F. Siepmann, J. Siepmann
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-12-01
主題:	PLGA Microparticles Drug release mechanism Experimental setup Swelling Agarose gel
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2590156723000646