Pathogenesis of Autoimmune Male Infertility: Juxtacrine, Paracrine, and Endocrine Dysregulation

According to global data, there is a male reproductive potential decrease. Pathogenesis of male infertility is often associated with autoimmunity towards sperm antigens essential for fertilization. Antisperm autoantibodies (ASAs) have immobilizing and cytotoxic properties, impairing spermatogenesis,...

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Bibliographic Details

Published in:	Pathophysiology
Main Authors:	Valeriy A. Chereshnev, Svetlana V. Pichugova, Yakov B. Beikin, Margarita V. Chereshneva, Angelina I. Iukhta, Yuri I. Stroev, Leonid P. Churilov
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	male infertility varicocele varicocelectomy spermatozoa sperm antigens antisperm autoantibodies
Online Access:	https://www.mdpi.com/1873-149X/28/4/30