Unveiling the intricacies of cardiac valve pathophysiology

IntroductionHeart valves have long been regarded as uncomplicated, avascular, and passive structures. However, we hypothesise that their structure and function are complex. Therefore, we have reviewed the available literature to gain a profound understanding of their cellular composition and (patho)...

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Bibliographic Details

Published in:	Frontiers in Cardiovascular Medicine
Main Authors:	Johannes H. Jedrzejczyk, Oline Hjertensgaard, Victor G. Puelles, J. Michael Hasenkam
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	valvular heart disease cardiac valves cardiac valve physiology cardiac valve pathophysiology valve endothelial cells valve interstitial cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1570271/full