Disassociation of muscle insulin signaling and insulin-stimulated glucose uptake during endotoxemia.

Lipopolysaccharide (LPS) elicits a strong immune response, which leads to the release of inflammatory cytokines. Increased cytokine production has been shown to impair insulin-mediated glucose disposal. LPS can alter other factors, such as muscle blood flow and insulin signaling in the myocyte, that...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Kimberly X Mulligan, R Tyler Morris, Yolanda F Otero, David H Wasserman, Owen P McGuinness
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	http://europepmc.org/articles/PMC3262801?pdf=render