An Acid-Sensitive Bone Targeting Delivery System Carrying Acacetin Prevents Osteoporosis in Ovariectomized Mice

One effective treatment for postmenopausal osteoporosis is to inhibit osteoclasts and subsequent bone resorption. In our study, we demonstrated that acacetin, a flavone with potential therapeutic effects in infections, cancers, and several metabolic disorders, inhibited osteoclast differentiation an...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Xiaochen Sun, Chenyu Song, Chenxi Zhang, Chunlei Xing, Juan Lv, Huihui Bian, Nanning Lv, Dagui Chen, Xin Dong, Mingming Liu, Li Su
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	osteoporosis autophagy acid-sensitive linker bone-targeting peptide postmenopausal osteoporosis
Online Access:	https://www.mdpi.com/1424-8247/16/1/2