Gpr18 agonist dampens inflammation, enhances myogenesis, and restores muscle function in models of Duchenne muscular dystrophy

Introduction: Muscle wasting in Duchenne Muscular Dystrophy is caused by myofiber fragility and poor regeneration that lead to chronic inflammation and muscle replacement by fibrofatty tissue. Our recent findings demonstrated that Resolvin-D2, a bioactive lipid derived from omega-3 fatty acids, has...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Junio Dort, Zakaria Orfi, Melissa Fiscaletti, Philippe M. Campeau, Nicolas A. Dumont
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-08-01
Subjects:	muscle inflammation bioactive lipid muscular dystrophies muscle stem cell (MuSC)
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1187253/full